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Did you mean part and bone marrow (10,160 results)?
Leishmania donovani singly deficient in HGPRT, APRT or XPRT are viable in vitro and within mammalian macrophages.
Boitz JM, Ullman B. Boitz JM, et al. Mol Biochem Parasitol. 2006 Jul;148(1):24-30. doi: 10.1016/j.molbiopara.2006.02.015. Epub 2006 Mar 15. Mol Biochem Parasitol. 2006. PMID: 16597468
Leishmania species express three phosphoribosyltransferase enzymes, hypoxanthine-guanine phosphoribosyltransferase (HGPRT), adenine phosphoribosyltransferase (APRT), and xanthine phosphoribosyltransferase (XPRT), which enable this genus to acquire purine nutrients from the …
Leishmania species express three phosphoribosyltransferase enzymes, hypoxanthine-guanine phosphoribosyltransferase (HGPRT), adenine phosphor …
Pattern of localization of primitive hematopoietic cells in vivo using a novel mouse model.
Bolante-Cervantes R, Li S, Sahota A, Tischfield JA, Zwerdling T, Stambrook PJ. Bolante-Cervantes R, et al. Exp Hematol. 1999 Aug;27(8):1346-52. doi: 10.1016/s0301-472x(99)00064-8. Exp Hematol. 1999. PMID: 10428512 Free article.
Bone marrow transplantation is increasingly used as a treatment for numerous immunologic, hematologic, and malignant disorders. ...Their presence also was visualized by autoradiography of paraffin-embedded tissue sections. APRT-positive c-kit-positive enriche …
Bone marrow transplantation is increasingly used as a treatment for numerous immunologic, hematologic, and malignant disorders …
Inborn errors of purine metabolism: clinical update and therapies.
Balasubramaniam S, Duley JA, Christodoulou J. Balasubramaniam S, et al. J Inherit Metab Dis. 2014 Sep;37(5):669-86. doi: 10.1007/s10545-014-9731-6. Epub 2014 Jun 28. J Inherit Metab Dis. 2014. PMID: 24972650
At present, treatments for the clinically significant defects of the purine pathway are restricted: purine 5'-nucleotidase deficiency with uridine; familial juvenile hyperuricaemic nephropathy (FJHN), adenine phosphoribosyl transferase (APRT) deficiency, hypoxanthine phosp …
At present, treatments for the clinically significant defects of the purine pathway are restricted: purine 5'-nucleotidase deficiency with u …
Purine metabolism in childhood acute lymphoblastic leukemia: biochemical markers for diagnosis and chemotherapy.
van Laarhoven JP, Spierenburg GT, Bakkeren JA, Schouten TJ, De Bruyn CH, Geerts SJ, Schretlen ED. van Laarhoven JP, et al. Leuk Res. 1983;7(3):407-20. doi: 10.1016/0145-2126(83)90105-4. Leuk Res. 1983. PMID: 6310274
Adenosine deaminase (ADA), purine nucleoside phosphorylase (PNP), 5'nucleotidase (5'NT), ecto-5'NT, hypoxanthine-guanine phosphoribosyltransferase(HGPRT), adenine phosphoribosyltransferase(APRT), adenosine kinase(AK), AMP deaminase (AMPD) and adenylate kinase(AdKin) activi …
Adenosine deaminase (ADA), purine nucleoside phosphorylase (PNP), 5'nucleotidase (5'NT), ecto-5'NT, hypoxanthine-guanine phosphoribosyltrans …
Preclinical toxicology studies with acyclovir: genetic toxicity tests.
Clive D, Turner NT, Hozier J, Batson AG, Tucker WE Jr. Clive D, et al. Fundam Appl Toxicol. 1983 Nov-Dec;3(6):587-602. doi: 10.1016/s0272-0590(83)80109-2. Fundam Appl Toxicol. 1983. PMID: 6662301
Negative results were obtained in the following in vitro tests: Ames Salmonella, plate incorporation and preincubation modification assays; E. coli polA+/polA- DNA repair; yeast (S. cerevisiae D4) gene conversion; Chinese hamster ovary cells (HGPRT, APRT loci and ouabain-r …
Negative results were obtained in the following in vitro tests: Ames Salmonella, plate incorporation and preincubation modification assays; …
Assays to predict the genotoxicity of the chromosomal mutagen etoposide -- focussing on the best assay.
Turner SD, Wijnhoven SW, Tinwell H, Lashford LS, Rafferty JA, Ashby J, Vrieling H, Fairbairn LJ. Turner SD, et al. Mutat Res. 2001 Jun 27;493(1-2):139-47. doi: 10.1016/s1383-5718(01)00170-x. Mutat Res. 2001. PMID: 11516723
This paper describes a series of assays that were employed to determine the in vivo genotoxicity of etoposide in a murine model system. The alkaline comet assay detected DNA damage in the bone marrow mononuclear compartment over the dose range of 10--100mg/kg and wa …
This paper describes a series of assays that were employed to determine the in vivo genotoxicity of etoposide in a murine model system. The …
Helical tomotherapy versus conventional radiation to deliver abdominopelvic radiation.
Choe J, Kulasekere R, Oddo D, Anthony S, Shin T, Murray M, Kunos CA. Choe J, et al. Technol Cancer Res Treat. 2012 Feb;11(1):49-56. doi: 10.7785/tcrt.2012.500234. Technol Cancer Res Treat. 2012. PMID: 22181331 Free article.
While whole abdominopelvic radiation (APRT) provided satisfactory radiation dosimetry for the treatment of cancers with peritoneal dissemination, APRT was abandoned due to unsatisfactory tumor control from necessary radiation shielding of vital organs. Our goal was …
While whole abdominopelvic radiation (APRT) provided satisfactory radiation dosimetry for the treatment of cancers with peritoneal di …
Distribution of enzymes of purine metabolism in lymphocytes of horse, Equus caballus.
Magnuson NS, Perryman LE, Mason PH, Marta KM. Magnuson NS, et al. Comp Biochem Physiol B. 1985;81(2):459-65. doi: 10.1016/0305-0491(85)90342-6. Comp Biochem Physiol B. 1985. PMID: 2990811
A microassay requiring as few as 2 X 10(5) cells per assay was developed for systematic analysis of 9 purine enzymes in lymphocytes from equine peripheral blood, spleen, lymph node, thymus and bone marrow. The activities of adenosine deaminase (ADA), purine nucleosi …
A microassay requiring as few as 2 X 10(5) cells per assay was developed for systematic analysis of 9 purine enzymes in lymphocytes from equ …
[Sideroblastic anemia associated with adenine phosphoribosyltransferase deficiency].
Mita M, Midorikawa J, Kokubun K, Uchida T. Mita M, et al. Rinsho Ketsueki. 1990 Oct;31(10):1701-5. Rinsho Ketsueki. 1990. PMID: 2255060 Japanese.
We report a case of acquired idiopathic sideroblastic anemia associated with adenine phosphoribosyltransferase (APRT) deficiency. A 72-year-old male had been troubled with urolithiasis since his teens. ...In June 1989, he was admitted to our hospital because of cerebral in …
We report a case of acquired idiopathic sideroblastic anemia associated with adenine phosphoribosyltransferase (APRT) deficiency. A 7 …
Adenine phosphoribosyl transferase polymorphism in baboons.
VandeBerg JL, Aivaliotis MJ. VandeBerg JL, et al. Biochem Genet. 1992 Aug;30(7-8):331-7. doi: 10.1007/BF00569323. Biochem Genet. 1992. PMID: 1445178
Two allelic isozymes of adenine phosphoribosyl transferase (APRT) were detected by starch gel electrophoresis of baboon hemolysates. ...The gene frequencies of five subspecies of baboons differed significantly. The activity of erythrocyte APRT is sufficiently high t …
Two allelic isozymes of adenine phosphoribosyl transferase (APRT) were detected by starch gel electrophoresis of baboon hemolysates. …